Isolated distal deep vein thrombosis: what we know and what we are doing

Isolated distal deep vein thrombosis: what we know and what we are doing.

Thromboses that are restricted to the infra-popliteal deep veins of the lower limbs (isolated distal deep vein thrombosis, IDDVT) are frequently diagnosed in subjects with suspected pulmonary embolism (PE; 7–10%) or DVT(4–15%), accounting for 31–56% of all diagnosed leg DVTs. Despite their frequency, IDDVTs still remain one of the most debated issues in the field of venous thromboembolism (VTE)...

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

Superior Capsule Reconstruction: What Do We Know?

The management of irreparable rotator cuff tears remains challenging. Since its introduction by Mihata in 2012, superiorcapsule reconstruction (SCR) has grown in popularity at an astonishingly rapid rate. The aim of this article is to providea comprehensive review of the available literature, in order to highlight what has so far been published on SCR,covering all aspects including biomechanica...

Why don't we know more about what we are doing?

There have been huge changes in science and technology in the past 30 years. We now understand the genetic basis of many diseases, and with the complete mapping of the genome, our knowledge will expand tremendously. We have CT, MRI, computer-guided surgery, gait analysis, and a host of other advances which have made medical care for our patients more effective. While these changes have profound...

Do We Know What We Do not Know? A Response to Celine Bonnet